Securing AI Using Zero Trust Principles
- By Cindy Green-Ortiz, Zig Zsiga, Saskia Laura Schröer
- Published Feb 2, 2026 by Cisco Press. Part of the Networking Technology: Security series.
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- Estimated Release: Feb 2, 2026
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- Copyright 2025
- Edition: 1st
- eBook
- ISBN-10: 0-13-836332-3
- ISBN-13: 978-0-13-836332-1
Securing Generative AI, LLMs, and ML Using Zero Trust Architecture
The first comprehensive guide to securing AI systems using Zero Trust architecture.
Artificial intelligence is no longer emerging; its embedded in almost every organizational interaction. From predictive analytics in healthcare or military operations, to generative models driving innovation in financial or governmental services, AI is powering critical decisions and business outcomes across every sector. But with transformative potential comes unprecedented risk. Threat actors are weaponizing AI to automate phishing, poison training data, manipulate outputs, and breach digital infrastructure at scale.
Zero Trust secures the AI path forward.
Unlike legacy trust but verify models, Zero Trust never assumes trust. Every identity, system, and interaction must be continuously verified. This architectural shift is essential to securing the entire AI lifecycle, from training data and models to endpoints, APIs, and decision-making pipelines.
This book shows you how to secure AI, responsibly and resiliently.
What Youll Learn
- Demystify the AI Ecosystem: Understand what generative AI, LLMs, embedded AI, Agentic AI, and machine learning really are and how theyre reshaping enterprise architecture.
- Recognize AI-specific Threats: Explore how adversaries are targeting AI models, training data, and inference pipelines and why conventional defenses fall short, including the shift to quantum technology.
- Embed Zero Trust in AI workflows: Apply microsegmentation, adaptive authentication, continuous verification, and telemetry, along with post quantum cryptographic algorithms, to protect AI across hybrid and cloud environments.
- Secure the AI Supply Chain: Harden training data, third-party integrations, model outputs, and API ecosystems to prevent compromise and misuse.
- Operationalize Strategy: Bridge the gap between executive intent and implementation with step-by-step guidance for aligning Zero Trust principles to real-world AI deployments.
Who This Book Is For
- Architects, engineers, leaders, and CXOs charged with safeguarding enterprise AI initiatives
- IT and data scientists embedding AI into core business workflows
- Risk, governance, and compliance teams navigating evolving AI regulations and frameworks (e.g., NIST AI RMF, EU AI Act, DORA, etc.)
- Cybersecurity professionals building operational resilience against AI-powered threats
Why Now?
AI adoption is accelerating faster than security frameworks can adapt. While organizations are still asking, What dont we know?, attackers are already acting. This book equips you with the frameworks, technical strategies, questions to ask, and operational playbooks to build secure, trustworthy AI systems, grounded in Zero Trust principles from day one.
Securing Generative AI, LLMs, and ML Using Zero Trust Architecture is your definitive guide for protecting the future of AI intelligently, holistically, and securely.